Translating Research into Action

TRACH advances research on communicable diseases and nutrition by translating scientific evidence into context-appropriate interventions for communities across Cameroon. Our work strengthens health outcomes for women and adolescents by ensuring evidence is accessible, actionable, and aligned with national priorities.

Research Projects

Evidence Translation Projects

Explore our research studies that generate actionable evidence for improving community health outcomes.

Malaria Prevention

Rethinking IPTp-SP Effectiveness in Pregnancy

Evidence from three health districts in the Mount Cameroon Area

Background

Intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp‑SP) is a cornerstone of malaria prevention. However, waning efficacy and possible drug resistance raise concerns about its continued effectiveness in reducing placental malaria (PM) and low birth weight (LBW).

465 pregnant women
Sample size
47%
≥3 doses coverage
18.5%
Placental malaria prevalence
7.3%
Low birth weight prevalence

Coverage Breakdown

≥ 3 doses: 47%
2 doses: 34.7%
1 dose: 18.3%
No SP: 7.1%

Resistance Monitoring

Resistance to sulfadoxine–pyrimethamine (SP) & Malaria in Pregnancy

Mount Cameroon Area

Background

Resistance to SP, used for intermittent preventive treatment in pregnancy (IPTp‑SP), is spreading, undermining protection for mothers and babies.

874 pregnant women screened
Sample size
7.7%
Microscopic parasitaemia
18.6%
Sub-microscopic parasitaemia
66.9%
SP-resistant mutations

Nutrition

Dietary Diversity and Maternal Anaemia in Mount Cameroon area

Mount Cameroon Area

Background

Maternal anaemia remains a major public health concern in the Mount Cameroon area. Poor dietary diversity is a key driver of anaemia during pregnancy limiting intake of protein and iron‑rich foods essential for healthy pregnancies.

1,014 pregnant women enrolled
Sample
10.4%
Adequate dietary diversity
89.6%
Poor diet diversity
40.9%
Anaemia prevalence
starchy staples (99.3%)
Most consumed
dairy (4.5%), eggs (8.3%)
Least consumed
12.39 g/dl vs 10.85 g/dl
Better diets = higher Hb
82.9%
Attributable risk (poor diet)

Nutrition
Manuscript in Preparation

Determinants of Dietary Intake and Maternal Nutritional Status

Mount Cameroon Area

Background

Poor maternal nutritional status during pregnancy is a critical public health problem with negative outcomes for both mother and child. In the Mount Cameroon area, dietary intake is strongly influenced by socio‑economic conditions, food security, nutritional knowledge, and antenatal care indicators.

400 pregnant women
Sample size
85.2%
Poor dietary diversity
54.5%
Poor nutrition knowledge
31.5%
Severe food insecurity

FGS Research

Addressing Female Genital Schistosomiasis (FGS) in Cameroon

Evidence from a Community-Based Pilot intervention study in Tiko

Background

Female genital schistosomiasis (FGS) is a neglected but serious reproductive health issue linked to urogenital schistosomiasis (UGS). In endemic areas like Tiko Health District (THD), many women and girls remain undiagnosed and untreated. This pilot study assessed the feasibility of syndromic screening and pre-emptive treatment with praziquantel (PZQ) in the prevention of FGS.

44 adolescent girls and women (ages 15–54)
Participants
61.4%
FGS symptom prevalence
31.8%
UGS prevalence
93%
PZQ reduced itching

Malaria Research
Planned Research

Mapping the Maternal–Foetal Interface in Malaria-Endemic Regions

Advanced Histological and Imaging Research (In Perspective)

Background

This proposed research aims to explore how malaria affects pregnancy by studying the maternal–fetal interface in fixed placental tissues collected from malaria-endemic areas. Using advanced histological and imaging techniques, we plan to understand how malaria parasites disrupt placental function, leading to complications such as maternal anaemia, low birth weight, and adverse neonatal outcomes. This work is currently in the planning phase and will contribute to global efforts to reduce the burden of malaria in pregnancy once initiated.

Placental Malaria
Research Focus
Histological & Imaging
Method
In Perspective
Status

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