Explore our complete portfolio of research studies generating evidence for improved community health outcomes in Cameroon.
Study examining the effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine.
Research on SP resistance mutations and their impact on malaria prevention in pregnant women.
Understanding the critical link between dietary diversity and maternal anaemia in the Mount Cameroon area.
Examining socio-economic determinants of dietary intake among pregnant women.
Community-based pilot study on syndromic screening and pre-emptive treatment with praziquantel.
Advanced histological and imaging research exploring how malaria affects pregnancy by studying the maternal–fetal interface in fixed placental tissues.
Ongoing program training peer educators and conducting community awareness campaigns.
Highlighting key collaborative research efforts conducted with national and international partners.
TRACH is proud to highlight the PREMISE clinical trial, a collaborative study conducted with clinical researchers from the University of Alabama, USA, on innovative approaches to protect maternal health in Cameroon.
This randomized, double-masked, placebo-controlled Phase IIB trial enrolled over 300 pregnant women living with HIV in Cameroon to test whether adding monthly azithromycin (AZ) to the standard daily trimethoprim-sulfamethoxazole (TMP-SMX) (also known as cotrimoxazole) prophylaxis could reduce malaria and sexually transmitted infections (STIs) at delivery.
This collaborative research underscores the importance of rigorous clinical trials in guiding maternal health policy. While azithromycin did not provide added benefit, the findings strengthen confidence in TMP-SMX prophylaxis and highlight the need for continued innovation in integrated malaria and STI prevention strategies for vulnerable populations.
In collaboration with ecologists from the University of Buea, University of Würzburg, Germany and the University of Lethbridge, Canada, we conducted a year-long study to understand how seasonal and environmental factors shape the abundance of Bulinus snails—the intermediate host of Schistosoma haematobium—in Tiko, a semi-urban endemic focus in the Mount Cameroon region.
Conclusion: This collaborative research provides actionable evidence for timely, environment-sensitive snail control programmes to reduce urogenital schistosomiasis transmission in Cameroon, while reinforcing vigilance against other trematode infections.
Our follow-up study on Female Genital Schistosomiasis (FGS) in Cameroon, conducted in collaboration with the INSIGHT consortium and supported by the Fogarty International Center, NIH Global Health Program, underscores the urgent burden of FGS in endemic regions. By combining advanced diagnostic methods with community-based engagement, the study demonstrates both the high prevalence of FGS and the critical need for accessible screening strategies that can be integrated into primary care and community health systems.
Through this collaborative effort, we are advancing community-driven solutions to safeguard women's reproductive health and strengthen health systems in affected communities.